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L-Tryptophan ethyl ester dilates small mesenteric arteries by inhibition of voltage-operated calcium channels in smooth muscle

BACKGROUND AND PURPOSE: L-tryptophan (L-W) is a precursor of the vasoconstrictor, 5-HT. However, acute administration of L-W ethyl ester (L-Wee) lowered blood pressure. The mechanism of action is unknown. This study compares the vascular effects of L-W and L-Wee in intact animals, isolated aortic ri...

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Bibliografske podrobnosti
Main Authors: Jadhav, Ashok, Liang, Wenbin, Balsevich, John, Bastin, Guillaume, Kroetsch, Jeff, Heximer, Scott, Backx, Peter H, Gopalakrishnan, Venkat
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Publishing Ltd 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3415651/
https://ncbi.nlm.nih.gov/pubmed/21951131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01693.x
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