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Circumvention of defective neutral amino acid transport in Hartnup disease using tryptophan ethyl ester.

Tryptophan ethyl ester, a lipid-soluble tryptophan derivative, was used to bypass defective gastrointestinal neutral amino acid transport in a child with Hartnup disease. The child's baseline tryptophan concentrations in serum (20 +/- 6 microM) and cerebrospinal fluid (1.0 +/- 0.2 microM) were persi...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Jonas, A J, Butler, I J
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303970/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2472426/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114141
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