Circumvention of defective neutral amino acid transport in Hartnup disease using tryptophan ethyl ester.

Tryptophan ethyl ester, a lipid-soluble tryptophan derivative, was used to bypass defective gastrointestinal neutral amino acid transport in a child with Hartnup disease. The child's baseline tryptophan concentrations in serum (20 +/- 6 microM) and cerebrospinal fluid (1.0 +/- 0.2 microM) were persi...

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Pubblicato in:	J Clin Invest
Autori principali:	Jonas, A J, Butler, I J
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1989
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303970/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2472426/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114141
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