Downregulation of GPR83 in the hypothalamic preoptic area reduces core body temperature and elevates circulating level of adiponectin

OBJECTIVE: The G protein-coupled receptor 83 (GPR83) was recently demonstrated in warm sensitive neurons (WSN) of the hypothalamic preoptic area (POA) that participate in temperature homeostasis. Thus, we investigated whether GPR83 may have a role in regulating core body temperature (CBT) by reducin...

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Main Authors: Dubins, Jeffrey S., Sanchez-Alavez, Manuel, Zhukov, Viktor, Sanchez-Gonzalez, Alejandro, Moroncini, Gianluca, Carvajal-Gonzalez, Santos, Hadcock, John R, Bartfai, Tamas, Conti, Bruno
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3415578/
https://ncbi.nlm.nih.gov/pubmed/22560055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.metabol.2012.03.015
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