Ccl22/MDC, is a prostaglandin dependent pyrogen, acting in the anterior hypothalamus to induce hyperthermia via activation of brown adipose tissue

CC Chemokine ligand 22 (Ccl22) is a selective, high affinity ligand at the CC chemokine receptor 4 (Ccr4). We have identified cDNAs encoding both ligand and receptor of the Ccl22-Ccr4 pair in cDNA libraries of the anterior hypothalamus/preoptic area (AH/POA) by PCR. The AH/POA is the key brain regio...

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Hlavní autoři: Osborn, Olivia, Sanchez-Alavez, Manuel, Dubins, Jeffrey S., Gonzalez, Alejandro Sanchez, Morrison, Brad, Hadcock, John R., Bartfai, Tamas
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033975/
https://ncbi.nlm.nih.gov/pubmed/21177120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2010.11.017
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