Direct pyrogenic input from prostaglandin EP3 receptor-expressing preoptic neurons to the dorsomedial hypothalamus

Fever is induced by the neuronal mechanism in the brain. Prostaglandin (PG) E(2) acts as a pyrogenic mediator in the preoptic area (POA) probably through the EP3 subtype of PGE receptor expressed on GABAergic neurons, and this PGE(2) action triggers neuronal pathways for sympathetic thermogenesis in...

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Hlavní autoři: Nakamura, Yoshiko, Nakamura, Kazuhiro, Matsumura, Kiyoshi, Kobayashi, Shigeo, Kaneko, Takeshi, Morrison, Shaun F.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2005
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2441892/
https://ncbi.nlm.nih.gov/pubmed/16367780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1460-9568.2005.04515.x
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