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Synapse Loss Induced by Interleukin-1β Requires Pre- and Post-Synaptic Mechanisms

Interleukin-1β (IL-1β) is an inflammatory cytokine that exerts marked effects on neuronal function and survival. Here we examined the effects of IL-1β on synapses between rat hippocampal neurons in culture using an imaging-based assay to quantify clusters of the scaffolding protein postsynaptic dens...

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Detalhes bibliográficos
Main Authors: Mishra, Anjuli, Kim, Hee Jung, Shin, Angela H., Thayer, Stanley A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3415563/
https://ncbi.nlm.nih.gov/pubmed/22311599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-012-9342-7
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