Essential role for retinoic acid in the promotion of CD4(+) T cell effector responses via retinoic acid receptor alpha

Vitamin A and its metabolite, retinoic acid (RA), have recently been implicated in the regulation of immune homeostasis via the peripheral induction of regulatory T cells. Here we show that RA is also required to elicit proinflammatory CD4(+) helper T cell responses to infection and mucosal vaccinat...

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Detalhes bibliográficos
Main Authors: Hall, J.A., Cannons, J.L., Grainger, J.R., Santos, L.M. Dos, Hand, T.W., Naik, S., Wohlfert, E.A., Chou, D.B., Oldenhove, G., Robinson, M., Grigg, M.E., Kastenmayer, R., Schwartzberg, P.L., Belkaid, Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3415227/
https://ncbi.nlm.nih.gov/pubmed/21419664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2011.03.003
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