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Site-specific Bacterial Chromosome Engineering: ΦC31 Integrase Mediated Cassette Exchange (IMCE)
The bacterial chromosome may be used to stably maintain foreign DNA in the mega-base range(1). Integration into the chromosome circumvents issues such as plasmid replication, plasmid stability, plasmid incompatibility, and plasmid copy number variance. This method uses the site-specific integrase fr...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MyJove Corporation
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3415167/ https://ncbi.nlm.nih.gov/pubmed/22453661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/3698 |
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