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Gated rotation mechanism of site-specific recombination by ϕC31 integrase

Integrases, such as that of the Streptomyces temperate bacteriophage ϕC31, promote site-specific recombination between DNA sequences in the bacteriophage and bacterial genomes to integrate or excise the phage DNA. ϕC31 integrase belongs to the serine recombinase family, a large group of structurally...

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Autores principales: Olorunniji, Femi J., Buck, Dorothy E., Colloms, Sean D., McEwan, Andrew R., Smith, Margaret C. M., Stark, W. Marshall, Rosser, Susan J.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511744/
https://ncbi.nlm.nih.gov/pubmed/23150546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1210964109
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