Lipid Loading of Human Vascular Smooth Muscle Cells Induces Changes in Tropoelastin Protein Levels and Physical Structure

Aggregated low-density lipoprotein (agLDL), one of the main LDL modifications in the arterial intima, contributes to massive intracellular cholesteryl ester (CE) accumulation in human vascular smooth muscle cells (VSMC), which are major producers of elastin in the vascular wall. Our aim was to analy...

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Detalhes bibliográficos
Main Authors: Samouillan, Valerie, Dandurand, Jany, Nasarre, Laura, Badimon, Lina, Lacabanne, Colette, Llorente-Cortés, Vicenta
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2012
Assuntos:
Proteins and Nucleic Acids
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3414902/
https://ncbi.nlm.nih.gov/pubmed/22947869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.06.034
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