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Predicting HLA Class I Non-Permissive Amino Acid Residues Substitutions

Prediction of peptide binding to human leukocyte antigen (HLA) molecules is essential to a wide range of clinical entities from vaccine design to stem cell transplant compatibility. Here we present a new structure-based methodology that applies robust computational tools to model peptide-HLA (p-HLA)...

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Detalhes bibliográficos
Main Authors: Binkowski, T. Andrew, Marino, Susana R., Joachimiak, Andrzej
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3414483/
https://ncbi.nlm.nih.gov/pubmed/22905104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041710
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