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The MUC1 Extracellular Domain Subunit Is Found in Nuclear Speckles and Associates with Spliceosomes
MUC1 is a large transmembrane glycoprotein and oncogene expressed by epithelial cells and overexpressed and underglycosylated in cancer cells. The MUC1 cytoplasmic subunit (MUC1-C) can translocate to the nucleus and regulate gene expression. It is frequently assumed that the MUC1 extracellular subun...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3414450/ https://ncbi.nlm.nih.gov/pubmed/22905162 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042712 |
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