A systematic comparison of quantitative high-resolution DNA methylation analysis and methylation-specific PCR

Assessment of DNA methylation has become a critical factor for the identification, development and application of methylation based biomarkers. Here we describe a systematic comparison of a quantitative high-resolution mass spectrometry-based approach (MassARRAY), pyrosequencing and the broadly used...

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Hlavní autoři: Claus, Rainer, Wilop, Stefan, Hielscher, Thomas, Sonnet, Miriam, Dahl, Edgar, Galm, Oliver, Jost, Edgar, Plass, Christoph
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2012
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Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3414395/
https://ncbi.nlm.nih.gov/pubmed/22647397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.20299
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