Association of cigarette smoking and CRP levels with DNA methylation in α-1 antitrypsin deficiency

Alpha-1 antitrypsin (AAT) deficiency and tobacco smoking are confirmed risk factors for Chronic Obstructive Pulmonary Disease. We hypothesized that variable DNA methylation would be associated with smoking and inflammation, as reflected by the level of C-Reactive Protein (CRP) in AAT-deficient subje...

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Detalhes bibliográficos
Main Authors: Siedlinski, Mateusz, Klanderman, Barbara, Sandhaus, Robert A., Barker, Alan F., Brantly, Mark L., Eden, Edward, McElvaney, N. Gerard, Rennard, Stephen I., Stocks, James M., Stoller, James K., Strange, Charlie, Turino, Gerard M., Campbell, Edward J., DeMeo, Dawn L.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3414392/
https://ncbi.nlm.nih.gov/pubmed/22617718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.20319
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