IL10 Polymorphisms Are Associated with Airflow Obstruction in Severe α(1)-Antitrypsin Deficiency

Severe α(1)-antitrypsin (AAT) deficiency is a proven genetic risk factor for chronic obstructive pulmonary disease (COPD), especially in individuals who smoke. There is marked variability in the development of lung disease in individuals homozygous (PI ZZ) for this autosomal recessive condition, sug...

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Main Authors: DeMeo, Dawn L., Campbell, Edward J., Barker, Alan F., Brantly, Mark L., Eden, Edward, McElvaney, N. Gerard, Rennard, Stephen I., Sandhaus, Robert A., Stocks, James M., Stoller, James K., Strange, Charlie, Turino, Gerard, Silverman, Edwin K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2008
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2176135/
https://ncbi.nlm.nih.gov/pubmed/17690329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2007-0107OC
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