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Functional coating of liposomes using a folate– polymer conjugate to target folate receptors
Folate-polymer-coated liposomes were developed for targeted chemotherapy using doxorubicin (DXR) as a model drug. Folate-poly(L-lysine) (F–PLL) conjugates with a folate modification degree of 16.7 mol% on epsilon amino groups of PLL were synthesized. DXR-loaded anionic liposomes were coated with F–P...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Dove Medical Press
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3414201/ https://ncbi.nlm.nih.gov/pubmed/22888227 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S32853 |
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