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Functional coating of liposomes using a folate– polymer conjugate to target folate receptors

Folate-polymer-coated liposomes were developed for targeted chemotherapy using doxorubicin (DXR) as a model drug. Folate-poly(L-lysine) (F–PLL) conjugates with a folate modification degree of 16.7 mol% on epsilon amino groups of PLL were synthesized. DXR-loaded anionic liposomes were coated with F–P...

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Detalhes bibliográficos
Main Authors: Watanabe, Kazuo, Kaneko, Makoto, Maitani, Yoshie
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3414201/
https://ncbi.nlm.nih.gov/pubmed/22888227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S32853
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