Structural Diversity in Conserved Regions Like the DRY-Motif among Viral 7TM Receptors—A Consequence of Evolutionary Pressure?

Several herpes- and poxviruses have captured chemokine receptors from their hosts and modified these to their own benefit. The human and viral chemokine receptors belong to class A 7 transmembrane (TM) receptors which are characterized by several structural motifs like the DRY-motif in TM3 and the C...

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Autores principales: Jensen, Ann-Sofie Mølleskov, Sparre-Ulrich, Alexander Hovard, Davis-Poynter, Nicholas, Rosenkilde, Mette Marie
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi Publishing Corporation 2012
Materias:
Review Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3414077/
https://ncbi.nlm.nih.gov/pubmed/22899926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/231813
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