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Binary Drugs: Conjugates of Purines and a Peptide That Bind to Both Adenosine and Substance P Receptors

A “functionalized congener” approach to adenosine receptor antagonists has provided a means to synthesize highly potent peptide conjugates of 1,3-dialkylxanthines. The antagonist XAC, such a functionalized xanthine amine congener, has been attached to a segment derived from the neurotransmitter pept...

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Detalhes bibliográficos
Main Authors: Jacobson, Kenneth A., Lipkowski, Andrzej W., Moody, Terry W., Padgett, William, Pijl, Evelyn, Kirk, Kenneth L., Daly, John W.
Formato: Artigo
Idioma:Inglês
Publicado em: 1987
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413949/
https://ncbi.nlm.nih.gov/pubmed/2441057
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