Transient but Not Stable ZEB1 Knockdown Dramatically Inhibits Growth of Malignant Pleural Mesothelioma Cells

BACKGROUND: The role of ZEB1, a master epithelial-tomesenchymal transition gene, in malignant pleural mesothelioma (MPM) is unclear. METHODS: The expression of ZEB1, E-cadherin, vimentin, and epithelial cell adhesion molecule (EpCAM) in 18 MPM cell lines and a normal pleural mesothelial cell line Me...

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Autors principals: Horio, Mihoko, Sato, Mitsuo, Takeyama, Yoshihiro, Elshazley, Momen, Yamashita, Ryo, Hase, Tetsunari, Yoshida, Kenya, Usami, Noriyasu, Yokoi, Kohei, Sekido, Yoshitaka, Kondo, Masashi, Toyokuni, Shinya, Gazdar, Adi F., Minna, John D., Hasegawa, Yoshinori
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413790/
https://ncbi.nlm.nih.gov/pubmed/22086445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1245/s10434-011-2142-0
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