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Knockdown of ZEB1, a master epithelial-to-mesenchymal transition (EMT) gene, suppresses anchorage-independent cell growth of lung cancer cells

We found that among four master epithelial-to-mesenchymal transition (EMT)-inducing genes (ZEB1, SIP1, Snail, and Slug) ZEB1expression was most significantly correlated with the mesenchymal phenotype (high Vimentin and low E-cadherin expression) in non-small cell lung cancer (NSCLC) cell lines and t...

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Detalhes bibliográficos
Main Authors: Takeyama, Yoshihiro, Sato, Mitsuo, Horio, Mihoko, Hase, Tetsunari, Yoshida, Kenya, Yokoyama, Toshihiko, Nakashima, Harunori, Hashimoto, Naozumi, Sekido, Yoshitaka, Gazdar, Adi F., Minna, John D., Kondo, Masashi, Hasegawa, Yoshinori
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3110825/
https://ncbi.nlm.nih.gov/pubmed/20452118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2010.04.008
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