Increased PK11195 PET binding in the cortex of patients with MS correlates with disability

OBJECTIVE: Activated microglia are thought to play a major role in cortical gray matter (GM) demyelination in multiple sclerosis (MS). Our objective was to evaluate microglial activation in cortical GM of patients with MS in vivo and to explore its relationship to measures of disability. METHODS: Us...

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Autori principali: Politis, Marios, Giannetti, Paolo, Su, Paul, Turkheimer, Federico, Keihaninejad, Shiva, Wu, Kit, Waldman, Adam, Malik, Omar, Matthews, Paul M., Reynolds, Richard, Nicholas, Richard, Piccini, Paola
Natura: Artigo
Lingua:Inglês
Pubblicazione: Lippincott Williams & Wilkins 2012
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413767/
https://ncbi.nlm.nih.gov/pubmed/22764258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e3182635645
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