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CULLIN-3 Controls TIMELESS Oscillations in the Drosophila Circadian Clock
Eukaryotic circadian clocks rely on transcriptional feedback loops. In Drosophila, the PERIOD (PER) and TIMELESS (TIM) proteins accumulate during the night, inhibit the activity of the CLOCK (CLK)/CYCLE (CYC) transcriptional complex, and are degraded in the early morning. The control of PER and TIM...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3413713/ https://ncbi.nlm.nih.gov/pubmed/22879814 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001367 |
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