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TIMELESS-dependent positive and negative autoregulation in the Drosophila circadian clock.
The timeless protein (TIM) is a central component of the circadian pacemaker machinery of the fruitfly Drosophila melanogaster. Both TIM and its partner protein, the period protein PER, show robust circadian oscillations in mRNA and protein levels. Yet the role of TIM in the rhythm generation mechan...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
1999
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1171160/ https://ncbi.nlm.nih.gov/pubmed/9927427 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.3.675 |
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