Presynaptic Selectivity of a Ligand for Serotonin 1A Receptors Revealed by In Vivo PET Assays of Rat Brain

A novel investigational antidepressant with high affinity for the serotonin transporter and the serotonin 1A (5-HT(1A)) receptor, called Wf-516 (structural formula: (2S)-1-[4-(3,4-dichlorophenyl)piperidin-1-yl]-3-[2-(5-methyl-1,3,4-oxadiazol-2-yl)benzo[b]furan-4-yloxy]propan-2-ol monohydrochloride),...

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Detalhes bibliográficos
Main Authors: Saijo, Takeaki, Maeda, Jun, Okauchi, Takashi, Maeda, Jun-ichi, Morio, Yasunori, Kuwahara, Yasuhiro, Suzuki, Masayuki, Goto, Nobuharu, Fukumura, Toshimitsu, Suhara, Tetsuya, Higuchi, Makoto
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413639/
https://ncbi.nlm.nih.gov/pubmed/22880045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042589
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