A Whole-Cell Computational Model Predicts Phenotype from Genotype

Understanding how complex phenotypes arise from individual molecules and their interactions is a primary challenge in biology that computational approaches are poised to tackle. We report a whole-cell computational model of the life cycle of the human pathogen Mycoplasma genitalium that includes all...

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Main Authors: Karr, Jonathan R., Sanghvi, Jayodita C., Macklin, Derek N., Gutschow, Miriam V., Jacobs, Jared M., Bolival, Benjamin, Assad-Garcia, Nacyra, Glass, John I., Covert, Markus W.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413483/
https://ncbi.nlm.nih.gov/pubmed/22817898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.05.044
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