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Single-particle tracking of immunoglobulin E receptors (FcεRI) in micron-sized clusters and receptor patches

When mast cells contact a monovalent antigen-bearing fluid lipid bilayer, IgE-loaded FcεRI receptors aggregate at contact points and trigger degranulation and the release of immune activators. We used two-color total internal reflection fluorescence microscopy and single-particle tracking to show th...

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Detalhes bibliográficos
Main Authors: Spendier, Kathrin, Lidke, Keith A., Lidke, Diane S., Thomas, James L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413461/
https://ncbi.nlm.nih.gov/pubmed/22265688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2012.01.013
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