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Single-particle tracking of immunoglobulin E receptors (FcεRI) in micron-sized clusters and receptor patches
When mast cells contact a monovalent antigen-bearing fluid lipid bilayer, IgE-loaded FcεRI receptors aggregate at contact points and trigger degranulation and the release of immune activators. We used two-color total internal reflection fluorescence microscopy and single-particle tracking to show th...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3413461/ https://ncbi.nlm.nih.gov/pubmed/22265688 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2012.01.013 |
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