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An AnkyrinG-Binding Motif Is Necessary and Sufficient for Targeting Na(v)1.6 Sodium Channels to Axon Initial Segments and Nodes of Ranvier
Neurons are highly polarized cells with functionally distinct axonal and somatodendritic compartments. Voltage-gated sodium channels Na(v)1.2 and Na(v)1.6 are highly enriched at axon initial segments (AISs) and nodes of Ranvier, where they are necessary for generation and propagation of action poten...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3413458/ https://ncbi.nlm.nih.gov/pubmed/22623668 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5434-11.2012 |
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