A Herpes Simplex Virus 1 (McKrae) Mutant Lacking the Glycoprotein K Gene Is Unable To Infect via Neuronal Axons and Egress from Neuronal Cell Bodies

We have shown that the herpes simplex virus 1 (HSV-1) gK gene is essential for efficient replication and spread in the corneal epithelium and trigeminal ganglion neuroinvasion in mice (A. T. David, A. Baghian, T. P. Foster, V. N. Chouljenko, and K. G. Kousoulas, Curr. Eye Res. 33:455–467, 2008). To...

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Autores principales: David, Andrew T., Saied, Ahmad, Charles, Anu, Subramanian, Ramesh, Chouljenko, Vladimir N., Kousoulas, Konstantin G.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Microbiology 2012
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413403/
https://ncbi.nlm.nih.gov/pubmed/22829677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00144-12
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