HIV-1 Gag co-opts a cellular complex containing DDX6, a helicase that facilitates capsid assembly

To produce progeny virus, human immunodeficiency virus type I (HIV-1) Gag assembles into capsids that package the viral genome and bud from the infected cell. During assembly of immature capsids, Gag traffics through a pathway of assembly intermediates (AIs) that contain the cellular adenosine triph...

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Detalhes bibliográficos
Main Authors: Reed, Jonathan C., Molter, Britta, Geary, Clair D., McNevin, John, McElrath, Julie, Giri, Samina, Klein, Kevin C., Lingappa, Jaisri R.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2012
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413349/
https://ncbi.nlm.nih.gov/pubmed/22851315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201111012
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