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A Temporospatial Map That Defines Specific Steps at Which Critical Surfaces in the Gag MA and CA Domains Act during Immature HIV-1 Capsid Assembly in Cells

During HIV-1 assembly, Gag polypeptides target to the plasma membrane, where they multimerize to form immature capsids that undergo budding and maturation. Previous mutational analyses identified residues within the Gag matrix (MA) and capsid (CA) domains that are required for immature capsid assemb...

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Autors principals: Robinson, Bridget A., Reed, Jonathan C., Geary, Clair D., Swain, J. Victor, Lingappa, Jaisri R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019110/
https://ncbi.nlm.nih.gov/pubmed/24623418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03609-13
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