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Self Renewal vs. Lineage Commitment of Embryonic Stem Cells: Protein Kinase C Signaling Shifts the Balance

The intricate molecular mechanisms that regulate embryonic stem (ES) cell pluripotency are incompletely understood. Prior research indicated that activation of JAK-STAT3 pathway or inhibition of ERK/GSK3 signaling maintains mouse ES cell (mESC) pluripotency. Here we demonstrate that inhibition of pr...

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Detaylı Bibliyografya
Asıl Yazarlar: Dutta, Debasree, Ray, Soma, Home, Pratik, Larson, Melissa, Wolfe, Michael W., Paul, Soumen
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413330/
https://ncbi.nlm.nih.gov/pubmed/21308862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.605
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