Altered subcellular localization of transcription factor TEAD4 regulates first mammalian cell lineage commitment

In the preimplantation mouse embryo, TEAD4 is critical to establishing the trophectoderm (TE)-specific transcriptional program and segregating TE from the inner cell mass (ICM). However, TEAD4 is expressed in the TE and the ICM. Thus, differential function of TEAD4 rather than expression itself regu...

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Detalhes bibliográficos
Main Authors: Home, Pratik, Saha, Biswarup, Ray, Soma, Dutta, Debasree, Gunewardena, Sumedha, Yoo, Byunggil, Pal, Arindam, Vivian, Jay L., Larson, Melissa, Petroff, Margaret, Gallagher, Patrick G., Schulz, Vincent P., White, Kenneth L., Golos, Thaddeus G., Behr, Barry, Paul, Soumen
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358889/
https://ncbi.nlm.nih.gov/pubmed/22529382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1201595109
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