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Catalytic and Structural Role of a Conserved Active Site Histidine in Berberine Bridge Enzyme
[Image: see text] Berberine bridge enzyme (BBE) is a paradigm for the class of bicovalently flavinylated oxidases, which catalyzes the oxidative cyclization of (S)-reticuline to (S)-scoulerine. His174 was identified as an important active site residue because of its role in the stabilization of the...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3413249/ https://ncbi.nlm.nih.gov/pubmed/22757961 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300411n |
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