TFIIS is required for the balanced expression of the genes encoding ribosomal components under transcriptional stress

Transcription factor IIS (TFIIS) stimulates RNA cleavage by RNA polymerase II by allowing backtracked enzymes to resume transcription elongation. Yeast cells do not require TFIIS for viability, unless they suffer severe transcriptional stress due to NTP-depleting drugs like 6-azauracil or mycophenol...

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Detalhes bibliográficos
Main Authors: Gómez-Herreros, Fernando, de Miguel-Jiménez, Lola, Morillo-Huesca, Macarena, Delgado-Ramos, Lidia, Muñoz-Centeno, María C., Chávez, Sebastián
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Gene Regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413141/
https://ncbi.nlm.nih.gov/pubmed/22544605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks340
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