Identification of high-confidence somatic mutations in whole genome sequence of formalin-fixed breast cancer specimens

The utilization of archived, formalin-fixed paraffin-embedded (FFPE) tumor samples for massive parallel sequencing has been challenging due to DNA damage and contamination with normal stroma. Here, we perform whole genome sequencing of DNA isolated from two triple-negative breast cancer tumors archi...

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Bibliographische Detailangaben
Hauptverfasser: Yost, Shawn E., Smith, Erin N., Schwab, Richard B., Bao, Lei, Jung, HyunChul, Wang, Xiaoyun, Voest, Emile, Pierce, John P., Messer, Karen, Parker, Barbara A., Harismendy, Olivier, Frazer, Kelly A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2012
Schlagworte:
Methods Online
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413110/
https://ncbi.nlm.nih.gov/pubmed/22492626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks299
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