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Conditional cooperativity in toxin–antitoxin regulation prevents random toxin activation and promotes fast translational recovery

Many toxin–antitoxin (TA) loci are known to strongly repress their own transcription. This auto-inhibition is often called ‘conditional cooperativity’ as it relies on cooperative binding of TA complexes to operator DNA that occurs only when toxins are in a proper stoichiometric relationship with ant...

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Detalhes bibliográficos
Main Authors: Cataudella, Ilaria, Trusina, Ala, Sneppen, Kim, Gerdes, Kenn, Mitarai, Namiko
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413109/
https://ncbi.nlm.nih.gov/pubmed/22495927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks297
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