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THE FIRST 5 SECONDS IN THE LIFE OF A CLATHRIN COATED PIT

Coated pits assemble by growth of a clathrin lattice, linked by adaptors to the underlying membrane. How does this process start? We used live-cell TIRF imaging, with single-molecule EGFP sensitivity and high temporal resolution, to detect arrival of the clathrin triskelions and AP2 adaptors that in...

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Autors principals: Cocucci, Emanuele, Aguet, François, Boulant, Steeve, Kirchhausen, Tom
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413093/
https://ncbi.nlm.nih.gov/pubmed/22863004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.05.047
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