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Cloned DNA probes regionally mapped to human chromosome 21 and their use in determining the origin of nondisjunction.
A number of unique sequence recombinant DNA clones were isolated from a recombinant DNA library constructed from DNA enriched for chromosome 21 by flow sorting. Of these, five were mapped to chromosome 21 using a somatic cell hybrid. Regional mapping of these probes and of a probe previously assigne...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
1985
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| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC341300/ https://ncbi.nlm.nih.gov/pubmed/3839305 |
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