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Markov Models of Use-Dependence and Reverse Use-Dependence during the Mouse Cardiac Action Potential
The fast component of the cardiac transient outward current, I(Ktof), is blocked by a number of drugs. The major molecular bases of I(Ktof) are Kv4.2/Kv4.3 voltage-gated potassium channels. Drugs with similar potencies but different blocking mechanisms have differing effects on action potential dura...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3412869/ https://ncbi.nlm.nih.gov/pubmed/22879935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042295 |
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