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The Role of the Subthalamic Nucleus in L-DOPA Induced Dyskinesia in 6-Hydroxydopamine Lesioned Rats

L-DOPA is the most effective treatment for Parkinson's disease (PD), but prolonged use leads to disabling motor complications including dyskinesia. Strong evidence supports a role of the subthalamic nucleus (STN) in the pathophysiology of PD whereas its role in dyskinesia is a matter of controv...

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Библиографические подробности
Главные авторы: Aristieta, Asier, Azkona, Garikoitz, Sagarduy, Ainhoa, Miguelez, Cristina, Ruiz-Ortega, José Ángel, Sanchez-Pernaute, Rosario, Ugedo, Luisa
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412805/
https://ncbi.nlm.nih.gov/pubmed/22880070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042652
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