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The locus coeruleus Is Directly Implicated in L-DOPA-Induced Dyskinesia in Parkinsonian Rats: An Electrophysiological and Behavioural Study

Despite being the most effective treatment for Parkinson’s disease, L-DOPA causes a development of dyskinetic movements in the majority of treated patients. L-DOPA-induced dyskinesia is attributed to a dysregulated dopamine transmission within the basal ganglia, but serotonergic and noradrenergic sy...

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Bibliographic Details
Main Authors: Miguelez, Cristina, Aristieta, Asier, Cenci, Maria Angela, Ugedo, Luisa
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3170382/
https://ncbi.nlm.nih.gov/pubmed/21931808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024679
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