Purification, crystallization and preliminary X-ray analysis of the DNA-binding domain of AdpA, the central transcription factor in the A-factor regulatory cascade in the filamentous bacterium Streptomyces griseus, in complex with a duplex DNA

Streptomyces griseus AdpA is the central transcription factor in the A-factor regulatory cascade and activates a number of genes that are required for both secondary metabolism and morphological differentiation, leading to the onset of streptomycin biosynthesis as well as aerial mycelium formation a...

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Autores principales: Yao, Ming Dong, Miyazono, Ken-ichi, Ohtsuka, Jun, Hirano, Setsu, Nagata, Koji, Horinouchi, Sueharu, Ohnishi, Yasuo, Tanokura, Masaru
Formato: Artigo
Lenguaje:Inglês
Publicado: International Union of Crystallography 2012
Materias:
Crystallization Communications
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412780/
https://ncbi.nlm.nih.gov/pubmed/22869129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309112026899
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