The RhoGAP protein Deleted in Liver Cancer 3 (DLC3) is essential for adherens junctions integrity

Epithelial cell–cell contacts are mediated by E-cadherin interactions, which are regulated by the balanced local activity of Rho GTPases. Despite the known function of Rho at adherens junctions (AJs), little is known about the spatial control of Rho activity at these sites. Here we provide evidence...

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Detalhes bibliográficos
Main Authors: Holeiter, G, Bischoff, A, Braun, A C, Huck, B, Erlmann, P, Schmid, S, Herr, R, Brummer, T, Olayioye, M A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412646/
https://ncbi.nlm.nih.gov/pubmed/23552697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2012.13
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