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LNA-based Oligonucleotide Electrotransfer for miRNA Inhibition

Micro-RNAs (miRNAs) are small regulatory RNAs that play an important role in disease development and progression and therefore represent a potential new class of therapeutic targets. However, an effective and safe clinical approach for miRNA inhibition remains elusive, primarily due to the lack of e...

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Autori principali: Chabot, Sophie, Orio, Julie, Castanier, Romain, Bellard, Elisabeth, Nielsen, Søren J, Golzio, Muriel, Teissié, Justin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412486/
https://ncbi.nlm.nih.gov/pubmed/22617110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2012.95
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