Sub-cellular temporal and spatial distribution of electrotransferred LNA/DNA oligomer

Low biological activity and inefficient targeted delivery in vivo have hindered RNA interference (RNAi)-based therapy from realising its full clinical potential. To overcome these hurdles, progresses have been made to develop new technologies optimizing oligonucleotides chemistry on one hand and ach...

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Detalhes bibliográficos
Main Authors: Orio, Julie, Bellard, Elisabeth, Baaziz, Houda, Pichon, Chantal, Mouritzen, Peter, Rols, Marie-Pierre, Teissié, Justin, Golzio, Muriel, Chabot, Sophie
Formato: Artigo
Idioma:Inglês
Publicado em: Journal of RNAi and Gene Silencing 2013
Assuntos:
Research Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3717327/
https://ncbi.nlm.nih.gov/pubmed/23946765
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