Sub-cellular temporal and spatial distribution of electrotransferred LNA/DNA oligomer

Low biological activity and inefficient targeted delivery in vivo have hindered RNA interference (RNAi)-based therapy from realising its full clinical potential. To overcome these hurdles, progresses have been made to develop new technologies optimizing oligonucleotides chemistry on one hand and ach...

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Autors principals: Orio, Julie, Bellard, Elisabeth, Baaziz, Houda, Pichon, Chantal, Mouritzen, Peter, Rols, Marie-Pierre, Teissié, Justin, Golzio, Muriel, Chabot, Sophie
Format: Artigo
Idioma:Inglês
Publicat: Journal of RNAi and Gene Silencing 2013
Matèries:
Research Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3717327/
https://ncbi.nlm.nih.gov/pubmed/23946765
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