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Dopamine D1/D5 Receptors Contribute to De Novo Hippocampal LTD Mediated by Novel Spatial Exploration or Locus Coeruleus Activity

The neurons of the locus coeruleus (LC) fire in response to novelty, and LC activation coupled with hippocampal afferent stimulation leads to long-term depression (LTD). The encoding of novel spatial information also involves activation of dopamine D1/D5 receptors. It is unclear if, or how, the nora...

詳細記述

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書誌詳細
主要な著者: Lemon, Neal, Manahan-Vaughan, Denise
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412443/
https://ncbi.nlm.nih.gov/pubmed/22038910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cercor/bhr297
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