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IL-17-Induced Act1-Mediated Signaling Is Critical for Cuprizone-Induced Demyelination
Cuprizone inhibits mitochondrial function and induces demyelination in the corpus callosum, which resembles pattern III lesions in multiple sclerosis patients. However, the molecular and cellular mechanism by which cuprizone induces demyelination remains unclear. Interleukin-17 (IL-17) secreted by T...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3412399/ https://ncbi.nlm.nih.gov/pubmed/22699909 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0841-12.2012 |
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